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Product Category:
Human Adenovirus Type5 (dE1/E3) expressing Pancreatic And Duodenal Homeobox 1 (PDX1) under CMV promoter.
Description:
Pancreatic And Duodenal Homeobox 1 (PDX1), pre-made adenovirus, ready to ship and ready to use format.
Gene Name:
Pancreatic And Duodenal Homeobox 1
ACCN:
BC111592
Gene ID:
3651
GI Number:
109939878
Fusion Tag:
No
Promoter:
CMV
Titer:
1x1011~1x1012 PFU/ml
Storage Buffer:
DMEM with 2.5% BSA, 2.5% glycerol
Background:
The protein encoded by PDX1 gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).
Documents:
