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| Product Category: | Human Adenovirus Type5 (dE1/E3) expressing mouse Calcium-regulated non-lysosomal thiol-protease. |
| Description: | Pre-made adenovirus for over-expression of mouse Calcium-regulated non-lysosomal thiol-protease fusion with GFP, ready to ship and ready to use format. |
| Gene: | Calcium-regulated non-lysosomal thiol-protease |
| NCBI Acc. #: | NM_007600.3 |
| Gene ID: | 12333 |
| GI Number: | 5031852 |
| Fusion Tag: | Fusion with GFP at C-terminal |
| Promoter: | CMV |
| Titer: | 1×1010~1×1011 PFU/ml |
| Storage Buffer: | DMEM with 2.5% BSA, 2.5% glycerol |
| Background: | The calpains including Calpain 1 (CAPN1), calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been found for this gene. Diseases associated with CAPN1 include Spastic Paraplegia 76, Autosomal Recessive and Spasticity. |
| Storage: | -80°C |
| Documents: | Please contact us to request the manual |
