Reactivity: | R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | SMARCE1 rabbit polyclonal antibody |
Gene Name: | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 |
Synonyms: | BRG1-associated factor 57, BAF57, Smarce1, Baf57 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Rat SMARCE1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Uniprot ID: | Q56A18 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Rat | 1: 1200-1: 2400 | brain |
Background
The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, SMARCE1, as an ER (estrogen receptor) subtype-selective modulator, regulates ER mediated transcription in a ligand-dependent manner and also directly binds to AR (androgen receptor) to alter its activity.
Images
Immunohistochemistry of paraffin embedded rat brain using smrcel (GB111306) at dilution of 1:1200 (400x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |