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Anti-CD109 Rabbit pAb (100 μl)
| Reactivity: | H,M & M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | CD109 antigen |
Synonyms: | CD109 molecule, CPAMD7, p180, Platelet specific Gov antigen, r150, RP11 525G3.1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Human CD109 |
Uniprot ID: | Q6YHK3 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane |
Predicted MW. / Observed MW. | 162 kDa / 190 kDa |
Product Usage Information
WB | Human, Mouse | 1: 500-1: 1000 | Jurkat, Siha, LWEIS, CT26.WT |
IHC/IF | Mouse, Rat | 1: 2000-1: 4000 | placenta, lung |
Background
CD109, also named as CPAMD7, is a member of the alpha2-macroglobulin/complement superfamily. It is a glycosylphosphatidylinositol (GPI)-linked cell surface glycoprotein of approximately 170kd which is found on the cell surface of platelets, activated T-cells, and endothelial cells. CD109 binds to and negatively regulates signaling of transforming growth factor beta (TGF-beta). CD109 has been identified as part of the TGF-beta receptor system in human keratinocytes. Up regulation of CD109 expression has been observed in several different types of tumor.
Images
| Western blot analysis of CD109 (GB115319) at dilution of 1: 1000 |
| Western blot analysis of CD109 (GB115319) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded mouse placenta using CD109 (GB115319) at dilution of 1: 3000 |
| Immunohistochemistry analysis of paraffin embedded mouse lung using CD109 (GB115319) at dilution of 1: 3000 |
| Immunohistochemistry analysis of paraffin embedded rat placenta using CD109 (GB115319) at dilution of 1: 3000 |
| Immunohistochemistry analysis of paraffin embedded rat lung using CD109 (GB115319) at dilution of 1: 3000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
