Reactivity: | M,R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | CD44 rabbit polyclonal |
Gene Name: | CD44 antigen |
Synonyms: | CD44, CDW44, CSPG8, ECMR III, Epican, HCELL, Heparan sulfate proteoglycan, Hermes antigen, HUTCH I, Hyaluronate receptor, IN, MC56, MDU2, MDU3, MIC4, MUTCH I, PGP-1, PGP I, Pgp1, Phagocytic glycoprotein I |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse CD44 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Predicted MW. | 82 kDa |
Observed MW. | 80-95 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human | 1: 500-1: 1000 | HeLa, A549, HUVEC |
IHC | Human | 1: 200-1: 400 | colon, tonsil |
IF | Human | 1: 200-1: 400 | esophagus |
Background
CD44 is a type I transmembrane glycoprotein that mediates cell-cell and cell-matrix interactions through its affinity for hyaluronic acid (HA) and possibly also through its affinity for other ligands. Adhesion with HA plays an important role in cell migration, tumor growth and progression. CD44 is also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis.
Images
Western blot analysis of CD44 (GB113500) at dilution of 1: 1000 | |
Immunohistochemistry analysis of paraffin-embedded human colon using CD44 (GB113500) at dilution of 1: 400 | |
Immunohistochemistry analysis of paraffin-embedded human tonsil using CD44 (GB113500) at dilution of 1: 400 | |
Immunofluorescent analysis of paraformaldehyde-fixed human esophagus using CD44 (GB113500) at dilution of 1: 400 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |