Reactivity: | M,R & H |
Applications: | WB & ICC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | Cytochrome c oxidase subunit 5A, mitochondrial |
Synonyms: | Cytochrome c oxidase polypeptide Va, Cox5a, Mitochondrial cytochromec oxidase subunit Va, Cytochrome c oxidase subunit 5A, COX |
Immunogen: | Recombinant protein corresponding to Mouse COX5A |
Uniprot ID: | P12787 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Mitochondrion, Mitochondrion inner membrane |
Predicted MW. / Observed MW. | 16 kDa / 16 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 500-1: 1000 | heart, brain, liver |
ICC/IF | Human | 1: 1500-1: 3000 | HeLa |
Background
COX5A(Cytochrome c oxidase subunit 5A,mitochondrial)is also named as COXVA and belongs to the cytochrome c oxidase subunit 5A family.It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane.This is the heme A-containing chain of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.The mature human COX Va polypeptide shares 35% and 95% protein sequence identity with the corresponding S. cerevisiae COX subunit VI and bovine COX Va, respectively.
Images
Western blot analysis of COX5A (GB111676) at dilution of 1: 1000 | |
Immunocytochemistry analysis of 4% paraformaldehyde fixed HeLa cells using COX5A (GB111676) at dilution of 1: 1500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |