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Anti-Calbindin Rabbit pAb (100 μl)
| Reactivity: | M,R & H,M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Calbindin |
Synonyms: | Calbindin D28, D-28K, PCD-29, Spot 35 protein, Vitamin D-dependent calcium-binding protein, avian-type, Calb1, CAB27, CALB1, CALB, Calbindin 1 |
Immunogen: | Recombinant protein corresponding to Mouse Calbindin |
Uniprot ID: | P12658 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus, Cytoplasm |
Predicted MW. / Observed MW. | 30 kDa / 30 kDa |
Images
Applications | Species | Dilution | Positive Sample |
WB | Mouse, Rat | 1: 500-1: 1000 | brain, kidney, pituitary |
IHC/IF | Human, Mouse, Rat | 1: 1000-1: 3000 | brain, kidney, renal cancer, small intestine |
Background
Calbindin 1 is a protein that in humans is encoded by the CALB1 gene. The protein encoded by this gene is a member of the calcium-binding protein superfamily that includes calmodulin and troponin C. Originally described as a 27 kDa protein, it is now known to be a 28 kDa protein. It contains four active calcium-binding domains, and has two modified domains that are thought to have lost their calcium binding capability. This protein is thought to buffer entry of calcium upon stimulation of glutamate receptors. Depletion of this protein was noted in patients with Huntington disease.
Images
| Western blot analysis of CALB1 (GB111211) at dilution of 1: 500 |
| Immunohistochemistry of paraffin embedded human renal cancer using CALB1 (GB111211) at dilution of 1: 1000 (400x lens) |
| Immunohistochemistry of paraffin embedded mouse brain using CALB1 (GB111211) at dilution of 1: 2000 (400x lens) |
| Immunohistochemistry of paraffin embedded mouse kidney using CALB1 (GB111211) at dilution of 1: 1000 (400x lens) |
| Immunohistochemistry of paraffin embedded rat brain using CALB1 (GB111211) at dilution of 1: 2000 (400x lens) |
| Immunohistochemistry of paraffin embedded rat kidney using CALB1 (GB111211) at dilution of 1: 2000 (400x lens) |
| Immunofluorescence of paraffin embedded mouse kidney using CALB1 (GB111211) at dilution of 1: 2000 (400x lens) |
| Immunofluorescence of paraffin embedded mouse small intestine using CALB1 (GB111211) at dilution of 1: 2000 (400x lens) |
| Immunofluorescence of paraffin embedded rat brain using CALB1 (GB111211) at dilution of 1: 2000 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
