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| Reactivity: | H,M |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | ELL rabbit polyclonal antibody |
Gene Name: | RNA polymerase II elongation factor ELL |
Synonyms: | Eleven-nineteen lysine-rich leukemia protein, Ell, elongation factor RNA polymerase II, RNA polymerase II elongation factor, Men |
Immunogen: | Recombinant protein corresponding to Mouse ELL |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 67 kDa |
Observed MW. | 80 kDa |
Uniprot ID: | P55199, O08856 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse | 1: 500-1: 1000 | NIH/3T3, HL-60, C2C12 |
Background
ELL is an elongation factor that inrecase the catalytic rate of RNA polymerase II transcription via suppressing transient pausing by the polymerase at multiple sites along the DNA. Also it's the second elongation factor to be involved in oncogenesis which is a transcription factor regulated by the product of the von Hippel-Lindau tumor suppressor. There are two transcirpts variants in mRNA level, one is 4.4kb transcript and the other is 2.8kb transcript.
Images
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Western blot analysis of ELL (GB111617) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
