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| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | GDNF rabbit polyclonal antibody |
Gene Name: | Glial cell line-derived neurotrophic factor |
Synonyms: | GDNF, ATF1, ATF2, HFB1-HSCR3, glial cell derived neurotrophic factor, ATF |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse GDNF |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Secreted |
Uniprot ID: | P39905, Q07731, P48540 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1:100-1:500 | brain, eye, ovary |
Background
This gene encodes a highly conserved neurotrophic factor. The recombinant form of this protein was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. The encoded protein is processed to a mature secreted form that exists as a homodimer. The mature form of the protein is a ligand for the product of the RET (rearranged during transfection) protooncogene.
Images
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Immunohistochemistry of paraffin embedded mouse brain using GDNF (GB11403) at dilution of 1:200 (400x lens) |
 | Immunohistochemistry of paraffin embedded rat brain using GDNF (GB11403) at dilution of 1:200 (400x lens) |
 | Immunofluorescence of paraffin embedded mouse brain using GDNF (GB11403) at dilution of 1:200 (400x lens) |
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Immunofluorescence of paraffin embedded mouse eye using GDNF (GB11403) at dilution of 1:200 (400x lens) |
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Immunofluorescence of paraffin embedded mouse ovary using GDNF (GB11403) at dilution of 1:200 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
