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Anti-HOXD12 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | HOXD12 rabbit polyclonal antibody |
Gene Name: | Homeobox protein Hox-D12 |
Synonyms: | Homeobox protein Hox-4.7, Homeobox protein Hox-5.6, Hoxd12, Hox-4.7, Hoxd-12 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse HOXD12 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 29 kDa |
Observed MW. | 29 kDa |
Uniprot ID: | P23812 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse, Rat | 1: 500-1: 1000 | skeletal muscle, liver, lung |
Background
The Hox proteins are a family of transcription factors that play a role in development and cellular differentiation by regulating downstream target genes. Specifically, the Hox proteins direct DNA-protein and protein-protein interactions that assist in determining the morphologic features associated with the anterior-posterior body axis. Hox proteins are involved in controlling axial patterning, leukemias and hereditary malformations. HoxD12 (homeobox D12), also known as HOX4H, is a 275 amino acid protein that localizes to the nucleus and contains one homeobox DNA-binding domain. One of several members of the homeobox superfamily, HoxD12 functions as a sequencespecific transcription factor that is important for the correct positioning of developing limb buds on the anterior-posterior axis.
Images
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Western blot analysis of HOXD12 (GB111513) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
