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Anti-KAT2/AadAT Rabbit pAb (100 μl)
| Reactivity: | M,R & M,R |
| Applications: | WB & IHC |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | KAT2/AadAT rabbit polyclonal |
Gene Name: | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial |
Synonyms: | 2 aminoadipate transaminase, AADAT, aminoadipate aminotransferase, KAT/AadAT, KAT2, KAT-2, KATII, Kynurenine aminotransferase II, kynurenine aminotransferase-2 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse KAT2/AadAT |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Predicted MW. | 48 kDa |
Observed MW. | 48 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 300-1: 600 | kidney |
IHC | Mouse, Rat | 1: 100-1: 200 | kidney |
Background
This gene encodes a protein that is highly similar to mouse and rat kynurenine aminotransferase II. The rat protein is a homodimer with two transaminase activities. One activity is the transamination of alpha-aminoadipic acid, a final step in the saccaropine pathway which is the major pathway for L-lysine catabolism. The other activity involves the transamination of kynurenine to produce kynurenine acid, the precursor of kynurenic acid which has neuroprotective properties. Several transcript variants encoding two different isoforms have been found for this gene.
Images
 | Western blot analysis of AadAT (GB113272) at dilution of 1: 600 |
| Immunohistochemistry analysis of paraffin-embedded mouse kidney using AadAT (GB113272) at dilution of 1: 200 |
| Immunohistochemistry analysis of paraffin-embedded rat kidney using AadAT (GB113272) at dilution of 1: 200 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
