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Anti-KCNAB2 Rabbit pAb (100 μl)
| Reactivity: | H,M,R & M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Voltage-gated potassium channel subunit beta-2 |
Synonyms: | AKR6A5, HKvbeta2, HKvbeta2.1, HKvbeta2.2, K(+) channel subunit beta 2, KCNA2B, KCNAB2, KCNK2, KV BETA 2 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse KCNAB2 |
Uniprot ID: | P62482 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, Cell membrane, Cell projection |
Predicted MW. / Observed MW. | 41 kDa / 40 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 1000-1: 2000 | brain, lung, kidney |
IHC/IF | Mouse, Rat | 1: 1000-1: 2400 | brain |
Background
Cytoplasmic potassium channel subunit that modulates the characteristics of the channel-forming alpha-subunits . Contributes to the regulation of nerve signaling, and prevents neuronal hyperexcitability . Promotes expression of the pore-forming alpha subunits at the cell membrane, and thereby increases channel activity. Promotes potassium channel closure via a mechanism that does not involve physical obstruction of the channel pore . Modulates the functional properties of KCNA4. Modulates the functional properties of KCNA5 . Enhances KCNB2 channel activity . Modulates the functional properties of KCNA5 . Binds NADPH and has NADPH-dependent aldoketoreductase activity.
Images
| Western blot analysis of KCNAB2 (GB114761) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded rat brain using KCNAB2 (GB114761) at dilution of 1: 2400 |
| Immunohistochemistry analysis of paraffin embedded mouse brain using KCNAB2 (GB114761) at dilution of 1: 2400 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
