Reactivity: | H,M,R & H,M,R |
Applications: | WB & IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | Far upstream element-binding protein 2 |
Synonyms: | FUSE-binding protein 2, KH type-splicing regulatory protein, KSRP, khsrp, ubp2 |
Immunogen: | Recombinant protein corresponding to Mouse KHSRP |
Uniprot ID: | Q3U0V1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, Nucleus |
Predicted MW. / Observed MW. | 77 kDa / 82 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 500-1: 1000 | brain, testis, colon |
IHC/IF | Human, Mouse, Rat | 1: 700-1: 1400 | brain, liver, testis |
Background
KHSRP, also named as FUBP2, KSRP and p75, belongs to the KHSRP family. It binds to the dendritic targeting element and may play a role in mRNA trafficking. KHSRP is a part of a ternary complex that binds to the downstream control sequence (DCS) of the pre-mRNA. It mediates exon inclusion in transcripts that are subject to tissue-specific alternative splicing. KHSRP may interact with single-stranded DNA from the far-upstream element (FUSE). May activate gene expression.
Images
Western blot analysis of KHRSP (GB111826) at dilution of 1: 1000 | |
Immunohistochemistry analysis of paraffin embedded rat liver using KHRSP (GB111826) at dilution of 1: 700 | |
Immunohistochemistry analysis of paraffin embedded mouse liver using KHRSP (GB111826) at dilution of 1: 700 | |
Immunohistochemistry analysis of paraffin embedded mouse brain using KHRSP (GB111826) at dilution of 1: 700 | |
Immunohistochemistry analysis of paraffin embedded mouse testis using KHRSP (GB111826) at dilution of 1: 700 | |
Immunohistochemistry analysis of paraffin embedded rat testis using KHRSP (GB111826) at dilution of 1: 700 | |
Immunofluorescent analysis of paraffin embedded rat testis using KHRSP (GB111826) at dilution of 1: 700 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |