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| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | MEF2C rabbit polyclonal antibody |
Gene Name: | Myocyte-specific enhancer factor 2C |
Synonyms: | Mef2c, MEF2C, C5DELq14.3, DEL5q14.3, myocyte enhancer factor 2C |
Immunogen: | Recombinant protein corresponding to Mouse MEF2C |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Uniprot ID: | Q06413, Q8CFN5, A0A096MJY4 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 250-1: 2000 | brain, cerebral infarction, Skeletal muscle, spinal cord |
Background
Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex.
Images
 | Immunohistochemistry of paraffin embedded mouse brain using MEF2C (GB11692) at dilution of 1:1000 (400x lens) |
 | Immunohistochemistry of paraffin embedded rat brain using MEF2C (GB11692) at dilution of 1:1000 (400x lens) |
 | Immunohistochemistry of paraffin embedded rat cerebral infarction using MEF2C (GB11692) at dilution of 1:1000 (400x lens) |
 |
Immunohistochemistry of paraffin embedded rat Skeletal muscle using MEF2C (GB11692) at dilution of 1:1000 (400x lens) |
| Immunofluorescence of paraffin embedded mouse spinal cord using MEF2C (GB11692) at dilution of 1:1000 (400x lens) |
| Immunofluorescence of paraffin embedded rat brain using MEF2C (GB11692) at dilution of 1:1000 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
