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Anti-Mad2L1 Rabbit pAb (100 μl)
| Reactivity: | M,R & M,R |
| Applications: | IHC & IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Mad2L1 rabbit polyclonal |
Gene Name: | Mitotic spindle assembly checkpoint protein MAD2A |
Synonyms: | Mitotic arrest deficient 2-like protein 1, MAD2-like protein 1, Mad2L1, Mad2a |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Mad2L1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Mouse, Rat | 1: 1000-1: 3000 | lung, ovary, lymph, testis, colon |
IF | Mouse, Rat | 1: 500-1: 1000 | pregnant mouse uterus, heart, lymph |
Background
The Mad2L1 is a component of the spindle-assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. Required for the execution of the mitotic checkpoint which monitors the process of kinetochore-spindle attachment and inhibits the activity of the anaphase promoting complex by sequestering CDC20 until all chromosomes are aligned at the metaphase plate.
Images
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Immunohistochemistry analysis of paraffin-embedded mouse lung using Mad2L1 (GB111185) at dilution of 1: 2000 |
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Immunohistochemistry analysis of paraffin-embedded rat lung using Mad2L1 (GB111185) at dilution of 1: 2000 |
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Immunohistochemistry analysis of paraffin-embedded mouse ovary using Mad2L1 (GB111185) at dilution of 1: 1400 |
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Immunohistochemistry analysis of paraffin-embedded rat ovary using Mad2L1 (GB111185) at dilution of 1: 1400 |
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Immunohistochemistry analysis of paraffin-embedded mouse lymph using Mad2L1 (GB111185) at dilution of 1: 2000 |
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Immunohistochemistry analysis of paraffin-embedded rat testis using Mad2L1 (GB111185) at dilution of 1: 1400 |
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Immunohistochemistry analysis of paraffin-embedded rat colon using Mad2L1 (GB111185) at dilution of 1: 2000 |
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Immunofluorescent analysis of paraffin-embedded pregnant mouse uterus using Mad2L1 (GB111185) at dilution of 1: 1000 |
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Immunofluorescent analysis of paraffin-embedded mouse heart using Mad2L1 (GB111185) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
