Your shopping cart is empty!
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | NF-kappa-B-repressing factor |
Synonyms: | ITBA4, NF kappa B repressing factor, NKRF, NRF, Protein ITBA4, Transcription factor NRF |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse NKRF |
Uniprot ID: | Q8BY02 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 78 kDa / 100 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 300-1: 1000 | brain |
Background
Interacts with a specific negative regulatory element (NRE) 5'-AATTCCTCTGA-3' to mediate transcriptional repression of certain NK-kappa-B responsive genes. Involved in the constitutive silencing of the interferon beta promoter, independently of the virus-induced signals, and in the inhibition of the basal and cytokine-induced iNOS promoter activity. Also involved in the regulation of IL-8 transcription .
Images
| Western blot analysis of NKRF (GB114665) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
