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Anti-PTBP2 Rabbit pAb (100 μl)
| Reactivity: | H,M,R & H,M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | PTBP2 rabbit polyclonal antibody |
Gene Name: | Polypyrimidine tract-binding protein 2 |
Synonyms: | Brain-enriched polypyrimidine tract-binding protein, Brain-enriched PTB, Nptb, Neural polypyrimidine tract-binding protein, RRM-type RNA-binding protein brPTB, Ptbp2, Brptb |
Immunogen: | Recombinant protein corresponding to Mouse PTBP2 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Predicted MW. | 57 kDa |
Observed MW. | 60 kDa |
Uniprot ID: | Q9UKA9, Q91Z31, Q66H20 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | heart, testis |
IHC/IF | Human, Mouse, Rat | 1: 600-1: 1200 | brain, glioma |
Background
PTBP2, also named as NPTB, PTB and PTBLP, is a RNA-binding protein which binds to intronic polypyrimidine tracts and mediates negative regulation of exons splicing. It may antagonize in a tissue-specific manner the ability of NOVA1 to activate exon selection. Beside its function in pre-mRNA splicing, PTBP2 plays also a role in the regulation of translation.
Images
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Western blot analysis of PTBP2 (GB111543) at dilution of 1: 500 |
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Immunofluorescence of paraffin embedded human glioma using PTBP2 (GB111543) at dilution of 1: 1000 (400x lens) |
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Immunofluorescence of paraffin embedded mouse brain using PTBP2 (GB111543) at dilution of 1: 1000 (400x lens) |
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Immunofluorescence of paraffin embedded rat brain using PTBP2 (GB111543) at dilution of 1: 1000 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
