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Anti-RING1 Rabbit pAb (100 μl)
| Reactivity: | H,M,R & H,M,R |
| Applications: | IHC & IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | RING1 rabbit polyclonal |
Gene Name: | E3 ubiquitin-protein ligase RING1 |
Synonyms: | Polycomb complex protein RING1, RING finger protein 1, RING-type E3 ubiquitin transferase RING1, Transcription repressor Ring1A, Ring1A, Rnf1, Ring1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse RING1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Human, Mouse, Rat | 1: 1800-1: 3600 | liver cancer, breast cancer, gastric cancer, esophagus, substantia nigra, spinal cord, heart |
IF | Human, Mouse, Rat | 1: 400-1: 800 | colon cancer, prostate, pancreas, skeletal muscle, thyroid |
Background
This gene belongs to the RING finger family, members of which encode proteins characterized by a RING domain, a zinc-binding motif related to the zinc finger domain. The gene product can bind DNA and can act as a transcriptional repressor. It is associated with the multimeric polycomb group protein complex. The gene product interacts with the polycomb group proteins BMI1, EDR1, and CBX4, and colocalizes with these proteins in large nuclear domains. It interacts with the CBX4 protein via its glycine-rich C-terminal domain.
Images
| Immunohistochemistry analysis of paraffin-embedded human liver cancer using Ring1A (GB112531) at dilution of 1: 3600 |
| Immunohistochemistry analysis of paraffin-embedded human breast cancer using Ring1A (GB112531) at dilution of 1: 3600 |
| Immunohistochemistry analysis of paraffin-embedded human gastric cancer using Ring1A (GB112531) at dilution of 1: 3600 |
| Immunohistochemistry analysis of paraffin-embedded human esophagus using Ring1A (GB112531) at dilution of 1: 3600 |
| Immunohistochemistry analysis of paraffin-embedded mouse substantia nigra using Ring1A (GB112531) at dilution of 1: 3600 |
| Immunohistochemistry analysis of paraffin-embedded rat substantia nigra using Ring1A (GB112531) at dilution of 1: 3600 |
| Immunohistochemistry analysis of paraffin-embedded mouse spinal cord using Ring1A (GB112531) at dilution of 1: 3600 |
| Immunohistochemistry analysis of paraffin-embedded rat spinal cord using Ring1A (GB112531) at dilution of 1: 3600 |
| Immunohistochemistry analysis of paraffin-embedded mouse heart using Ring1A (GB112531) at dilution of 1: 3600 |
| Immunohistochemistry analysis of paraffin-embedded rat heart using Ring1A (GB112531) at dilution of 1: 3600 |
| Immunofluorescent analysis of paraformaldehyde-fixed human colon cancer using Ring1A (GB112531) at dilution of 1: 800 |
| Immunofluorescent analysis of paraformaldehyde-fixed human prostate using Ring1A (GB112531) at dilution of 1: 800 |
| Immunofluorescent analysis of paraformaldehyde-fixed mouse pancreas using Ring1A (GB112531) at dilution of 1: 800 |
| Immunofluorescent analysis of paraformaldehyde-fixed rat skeletal muscle using Ring1A (GB112531) at dilution of 1: 800 |
| Immunofluorescent analysis of paraformaldehyde-fixed rat thyroid using Ring1A (GB112531) at dilution of 1: 800 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
