Your shopping cart is empty!
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Mouse |
| Clonality: | Monoclonal |
| Gene Name: | Rho-associated protein kinase 2 |
Synonyms: | Rho kinase 2, coiled-coil-containing protein kinase 2, ROCK-II, KIAA0619, Rho-associated, p164 ROCK 2, Rock2m, ROKalpha, Rho kinase 2 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse ROCK2 |
Uniprot ID: | P70336 |
Isotype: | IgG2a,κ |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 161 kDa / 180 kDa |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | brain, liver, colon |
Background
ROCK2 is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. It is an isozyme of ROCK1, is a target for the small GTPase Rho. ROCK2 is localized in both cytoplasm and nucleus, and the nucleus-localized ROCK2 can target p300 for phosphorylation to regulate its acetyltransferase activity.
Images
 | Western blot analysis of ROCK2 (GB121692) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
