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Anti-Spinophilin/Neurabin 2 Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Spinophilin/Neurabin 2 rabbit polyclonal antibody |
Gene Name: | Neurabin-2 |
Synonyms: | Neurabin-II, Protein phosphatase 1 regulatory subunit 9B, Spinophilin, Ppp1r9b, SPINO, Spn |
Immunogen: | Recombinant protein corresponding to Mouse Spinophilin |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 90 kDa |
Observed MW. | 130 kDa |
Uniprot ID: | Q96SB3, Q6R891, O35274 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | cerebellum |
Background
PPP1R9B, also named as PPP1R6, Neurabin-II and Spinophilin, seems to act as a scaffold protein in multiple signaling pathways. It modulates excitatory synaptic transmission and dendritic spine morphology. PPP1R9B binds to actin filaments (F-actin) and shows cross-linking activity. It may play an important role in linking the actin cytoskeleton to the plasma membrane at the synaptic junction. PPP1R9B plays a role in regulation of G-protein coupled receptor signaling, including D2Rs and alpha-adrenergic receptors.
Images
| Western blot analysis of Ppp1r9b (GB111956) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
