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Anti-Synaptophysin Mouse mAb (100 μl)
| Reactivity: | M,R & H,M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Mouse |
| Clonality: | Monoclonal |
| Gene Name: | Synaptophysin |
Synonyms: | Syp, SYP, MRX96, MRXsynaptophysin |
Immunogen: | Recombinant protein corresponding to Human Synaptophysin |
Uniprot ID: | P08247 |
Isotype: | IgG2b,κ |
Purity: | Affinity purification |
Subcellular location: | Cell membrane, Cytoplasm |
Predicted MW. / Observed MW. | 34 kDa / 38 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 500-1: 1000 | brain, cerebral cortex, hippocampus |
IHC/IF | Human, Mouse, Rat | 1: 500-1: 1500 | neuroendocrine neoplasms, glioblastoma multiforme, brain, cerebellum, brain |
Background
Synaptophysin is an integral membrane protein of small synaptic vesicles in brain and endocrine cells. The protein also binds cholesterol and is thought to direct targeting of vesicle-associated membrane protein 2 (synaptobrevin) to intracellular compartments. Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity.
Images
| Western blot analysis of synaptophysin-1 (GB12814) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded human neuroendocrine neoplasms using synaptophysin (GB12814) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded human glioblastoma multiforme using synaptophysin (GB12814) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded mouse brain using synaptophysin (GB12814) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded mouse cerebellum using synaptophysin (GB12814) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded rat brain using synaptophysin (GB12814) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
