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Anti-TWEAK Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | TWEAK rabbit polyclonal antibody |
Gene Name: | Tumor necrosis factor ligand superfamily member 12 |
Synonyms: | TNF-related weak inducer of apoptosis, TWEAK, Tnfsf12, APO3 ligand, DR3LG, TNFSF12 protein, APO3/DR3 ligand |
Immunogen: | Recombinant protein corresponding to Mouse TWEAK |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane, Secreted |
Uniprot ID: | O54907 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 500-1: 2000 | brain |
Background
TNF-related weak inducer of apoptosis (TWEAK) is a member of the tumor necrosis factor superfamily (TNFSF) of structurally related cytokines. Like most other members of this family, TWEAK is a cell surface-associated type II transmembrane protein although a smaller, biologically active form can also be generated by cleavage near the cell membrane. TWEAK has multiple biological activities, including stimulation of cell growth and angiogenesis, induction of inflammatory cytokines, in addition to stimulation of apoptosis.
Images
| Immunohistochemistry of paraffin embedded mouse brain using TWEAK (GB111772) at dilution of 1:1000 (300x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
