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| Reactivity: | M,R & H,M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Yes1 rabbit polyclonal antibody |
Gene Name: | Tyrosine-protein kinase Yes |
Synonyms: | Proto-oncogene c-Yes, p61-Yes, P61 YES, YES1, YES, Cellular Yes1 protein, HsT441, Proto oncogene tyrosine protein kinase YES, Proto-oncogene c-Yes, Tyrosine-protein kinase Yes |
Immunogen: | Recombinant protein corresponding to Mouse Yes1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 61 kDa |
Observed MW. | 61 kDa |
Uniprot ID: | P07947 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human | 1: 500-1: 1000 | U87, SW480, Jurkat |
Background
This gene is the cellular homolog of the Yamaguchi sarcoma virus oncogene. The encoded protein has tyrosine kinase activity and belongs to the src family of proteins. After Src, Yes is the most widely expressed member of the Src family of nonreceptor tyrosine kinases. Src family kinases regulate an array of cellular processes, including growth factor signaling, cytoskeleton dynamics, and cell proliferation.
Images
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Western blot analysis of YES1 (GB111450) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
