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| Product Category: | Human Adenovirus Type5 (dE1/E3) expressing SMARCB1 gene under CMV promoter. |
| Description: | SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily B, Member 1, pre-made adenovirus, ready to ship and ready to use format. |
| Gene: | SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily B, Member 1 |
| NCBI Acc. #: | CR456581 |
| Gene ID: | 6598 |
| GI Number: | 47678692 |
| Fusion Tag: | No |
| Promoter: | CMV |
| Storage Buffer: | DMEM with 2.5% BSA, 2.5% glycerol |
| Background: | The SWI-SNF complex is involved in the activation of transcription via the remodeling of nucleosome structure in an ATP-dependent manner. Brm (also designated SNF2alpha) and Brg-1 (also designated SNF2beta) are the ATPase subunits of the mammalian SWI-SNF complex. Brm, Brg-1, Ini1 (integrase interactor 1, also designated SNF5), BAF155 (also designated SRG3) and BAF170 are thought to comprise the functional core of the SWI-SNF complex. Addition of Ini1, BAF155 and BAF170 to Brg-1 appears to increase remodeling activity. Other complex subunits are thought to play regulatory roles. hSNF2L and hSNF2H both appear to be homologs of Drosophila ISWI, a Brm related ATPase that is present in chromatin remodeling complexes other than SWI/SNF, including the NURF (nucleosome remodeling factor). |
| Documents: | Please contact us to request the manual |
