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| Description: | Carboxy-H2DCFDA [5-(and 6)-Carboxy-2′,7′-dichlorodihydrofluorescein diacetate] is a chemically reduced analogue of fluorescein used as an indicator for reactive oxygen species (ROS) in cells. Upon cleavage of the acetate groups by intracellular esterases and oxidation, the nonfluorescent Carboxy-H2DCFDA is converted to the highly fluorescent 5-(and 6)-carboxy-2',7'-dichlorofluorescein, with additional negative charges that impede its leakage out of the cell. |
| Specifications: | 1. Ex/Em: 495/529 nm 2. Detection Method: Fluorescent 3. Molecular Formula: C25H16Cl2O9 4. Molecular Weight: 531.30 |
| Applictions: | Probe for ROS |
| Component: | 1. Carboxy-H2DCFDA: 25 mg |
| Storage: | At -20°C and protect from light |
| Download: | Manual |